Split-Thickness Skin Graft Reconstruction Following Post-Traumatic Hand Infection: Case Report and Literature Review

Main Article Content

Irad Antonio Zuñiga-Salazar
Felipe Alarcón-Estrada
Alejandro Herbert Oliva-Arvizu
Brenda Aracely Saenz-Medina
Diego Cabeza-Gracia
Miriam Melina Vargas-Mejía
Jocelyn Galindo-Najera
Marlen González-Santana
Mauricio Alonso Espinosa-Romero
Elisa Taynisha Leal-Cabrera

Abstract

Background: Hand trauma resulting from occupational machinery accidents represents complex high-energy injuries frequently associated with contamination, tissue necrosis, and soft-tissue infection, which can hinder early cutaneous coverage and compromise functional outcomes. Appropriate management requires effective control of the septic focus, adequate preparation of the recipient bed, and timely reconstruction using reliable coverage techniques.


Case Report: We report the case of a 34-year-old left-hand–dominant male who sustained a traumatic avulsion injury to the left hand during occupational activity. Initial management consisted of primary wound closure; however, the patient subsequently developed a soft-tissue infection with formation of a dorsal abscess, which required surgical drainage and broad-spectrum antibiotic therapy adjusted according to clinical progression. Following serial surgical debridements, a dorsal cutaneous defect measuring 14 × 7 cm with viable granulation tissue was obtained. Definitive coverage was achieved using a split-thickness skin graft (0.30 mm) harvested with an electric dermatome. At five days postoperatively, adequate graft integration was documented, with no evidence of necrosis or persistent infection, allowing the initiation of early functional rehabilitation.


Discussion: Post-traumatic infections of the hand require prompt surgical drainage and targeted antibiotic therapy, as pharmacologic treatment alone is insufficient in the presence of purulent collections. Adequate preparation of the recipient bed represents the most important determinant of successful graft take. In extensive dorsal defects, split-thickness skin grafts offer higher rates of integration due to their lower metabolic demand and greater tolerance to irregularities of the wound bed. Graft incorporation occurs through the sequential phases of plasmatic imbibition, inosculation, and maturation. Early clinical evaluation is therefore essential to identify potential complications and prevent functional impairment.


Conclusion: Sequential control of infection followed by coverage with a split-thickness skin graft represents an effective and safe strategy for the management of extensive dorsal hand defects resulting from occupational trauma. This approach provides stable cutaneous coverage and facilitates early functional rehabilitation.

Article Details

How to Cite
Irad Antonio Zuñiga-Salazar, Felipe Alarcón-Estrada, Alejandro Herbert Oliva-Arvizu, Brenda Aracely Saenz-Medina, Diego Cabeza-Gracia, Miriam Melina Vargas-Mejía, Jocelyn Galindo-Najera, Marlen González-Santana, Mauricio Alonso Espinosa-Romero, and Elisa Taynisha Leal-Cabrera. 2026. “Split-Thickness Skin Graft Reconstruction Following Post-Traumatic Hand Infection: Case Report and Literature Review”. International Journal of Medical Science and Clinical Research Studies 6 (03):627-33. https://doi.org/10.47191/ijmscrs/v6-i3-33.
Section
Articles

References

I. Braza, M. E., & Fahrenkopf, M. P. (2025). Split-thickness skin grafts. StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK551561/

II. Crowe, C. S., Massenburg, B. B., Morrison, S. D., Chang, J., & Abady, G. G. (2020). Global trends of hand and wrist trauma: A systematic analysis of fracture and digit amputation using the Global Burden of Disease 2017 study. Injury Prevention, 26(Suppl 2), i115–i124. https://doi.org/10.1136/injuryprev-2019-043495

III. Dailiana, Z. H., Rigopoulos, N., Varitimidis, S., & Malizos, K. N. (2018). Purulent flexor tenosynovitis: Factors influencing the functional outcome. Journal of Hand Surgery (European Volume), 43(5), 509–514.

https://doi.org/10.1177/1753193417740875

IV. Fufa, D. T., Calfee, R. P., Wall, L. B., & Zeng, W. (2013). Acute hand infections. Journal of Hand Surgery, 38(12), 2458–2468.

https://doi.org/10.1016/j.jhsa.2013.09.028

V. King, V. M., & Tosti, R. (2023). Infection management for the hand surgeon. Hand Clinics, 39(2), 147–159.

https://doi.org/10.1016/j.hcl.2023.01.004

VI. Milner, S. M., & Choudhry, M. A. (2024). Skin grafting of the dorsum of the hand. ePlasty, 24,

e15.

VII. Ramsey, M. L., & Dove, C. R. (2025). Full-thickness skin grafts. StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK532875/

VIII. Shores, J. T., Higgins, J. P., & Lee, W. P. A. (2011). Tendon and soft tissue coverage of the hand. Plastic and Reconstructive Surgery, 127(3), 136e–151e. https://doi.org/10.1097/PRS.0b013e318205f3e0

IX. Song, E. C., & Tosti, R. (2024). Diagnosis and management of hand infections. Journal of Hand Surgery, 49(4), 345–357. https://doi.org/10.1016/j.jhsa.2023.10.012

X. Thompson, P. W., & Herndon, D. N. (2017). Principles of burn reconstruction and skin grafting. Plastic and Reconstructive Surgery, 139(3), 688e–698e. https://doi.org/10.1097/PRS.0000000000003110

XI. Weinzweig, N., & Gonzalez, M. (2012). Surgical infections of the hand and upper extremity: A comprehensive review. Plastic and Reconstructive Surgery, 129(4), 795e–806e. https://doi.org/10.1097/PRS.0b013e3182442355

XII. Wu, Z., Zhang, X., & Zhang, Y. (2018). The epidemiology of acute occupational hand injuries treated in emergency departments. Ulus Travma Acil Cerrahi Dergisi, 24(3), 256–262.

https://doi.org/10.5505/tjtes.2017.59020

XIII. Zubowicz, V. N., & Gravier, M. (2014).

Management of soft tissue defects of the hand. Hand Clinics, 30(2), 193–205. https://doi.org/10.1016/j.hcl.2013.12.006

XIV. Khan, W., Agarwal, M., & Funk, L. (2016). Skin grafting in hand reconstruction: A review of indications and outcomes. Journal of Hand Surgery (European Volume), 41(6), 628–636.

https://doi.org/10.1177/1753193415620121

XV. Peterson, B. C., Mangiapani, D. S., & Kakar, S. (2019). Modern management of hand infections. Hand Clinics, 35(1), 1–12.

https://doi.org/10.1016/j.hcl.2018.08.001

Most read articles by the same author(s)