Functional Evaluation of Hyaluronic Acid and Collagen Infiltration in Gonarthrosis II in a Secondlevel Hospital
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Abstract
Background: Knee osteoarthritis is a leading cause of pain and disability, with increasing incidence associated with aging and obesity. Intra-articular therapies such as collagen and hyaluronic acid injections have emerged as valuable alternatives for symptom relief and functional improvement in patients with gonarthrosis.
Objective: To evaluate functional outcomes following intra-articular infiltration with hyaluronic acid and collagen in patients with grade II gonarthrosis treated at the General Regional Hospital of Orizaba.
Methods: A descriptive, prospective, and analytical study was conducted in 120 patients diagnosed with grade II gonarthrosis who received intra-articular infiltration with either HA or collagen. Functional assessment was performed using the validated Spanish version of the WOMAC scale (Cronbach’s alpha 0.92). Patients were followed for six weeks. Data analysis was conducted with SPSS v25, using measures of central tendency and dispersion, frequency distribution, Pearson’s chi-square test, and Student’s t-test for independent variables. A p value < 0.05 was considered statistically significant.
Results: Both treatment groups demonstrated improvement in functional scores at six weeks. Comparative analysis showed functional benefits in both therapies, with differential patterns of improvement between and collagen.
Conclusions: Intra-articular infiltration with hyaluronic acid and collagen provides functional improvement in patients with grade II gonarthrosis. These therapies represent effective non-surgical management options, supporting their clinical utility in early-stage.
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